Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666969 | 0.88 | PTDSS1 (0.40) | PTGDRMAPTIL4I1 | |
| SCHEMBL31667552 | 0.86 | NOS1 (0.51) | PDE10AIL4I1MAOAMAOBCREBBP | |
| SCHEMBL31666978 | 0.85 | GRIN2D (0.41) | PTGDRPDE10AIL4I1MAOAMAOB | |
| SCHEMBL31667564 | 0.85 | IL4I1 (0.39) | PTGDRPDE10AIL4I1MAOAMAOB | |
| SCHEMBL31666950 | 0.85 | IL4I1 (0.39) | PTGDRPDE10AIL4I1MAOAMAOB | |
| SCHEMBL31667589 | 0.85 | NOS1 (0.41) | MAPTTDP1IL4I1NOS1HTR1A | |
| SCHEMBL31667541 | 0.85 | IL4I1 (0.39) | PTGDRPDE10AIL4I1CREBBPNOS1 | |
| SCHEMBL31667528 | 0.85 | IL4I1 (0.39) | PTGDRPDE10AIL4I1CREBBPNOS1 | |
| SCHEMBL31667115 | 0.84 | IL4I1 (0.46) | MAPTTDP1MAPK1IL4I1NOS1 | |
| SCHEMBL31667642 | 0.84 | IL4I1 (0.46) | MAPTTDP1MAPK1IL4I1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| EP-4590674-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | PTGDR 736/4885PDE10A 1264/4885SMN1; SMN2 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.