Formic Acid

Formic Acid

SCHEMBL31546376

COc1ccc(-c2noc(N3CCN(C(=O)NCCCN4CCC(F)(Cc5ccccn5)CC4)CC3)n2)cc1.O=CO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.49
▸ MAPT P10636 5/20 0.49
▸ HTT P42858 4/20 0.49
▸ SMN1; SMN2 Q16637 4/20 0.49
▸ TP53 P04637 4/20 0.49
▸ KDM4E B2RXH2 2/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ NPC1 O15118 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ HTR1A P08908 2/20 0.44
▸ HTR7 P34969 2/20 0.44
▸ THRB P10828 1/20 0.44
▸ TSHR P16473 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667734 0.97 LMNA (0.51) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL30584825 0.89 LMNA (0.52) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL31546410 0.86 LMNA (0.56) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584958 0.86 MAPT (0.52) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667398 0.86 LMNA (0.55) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667543 0.83 LMNA (0.58) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL30584933 0.81 TSHR (0.65) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL30584798 0.80 MEN1 (0.56) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584805 0.78 LMNA (0.48) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584818 0.76 MEN1 (0.60) LMNAMAPTHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 LMNA 1344/4885MAPT 2999/4885HTT 2290/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1344/4885MAPT 2999/4885HTT 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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