SCHEMBL31667734

SCHEMBL31667734

COc1ccc(-c2noc(N3CCN(C(=O)NCCCN4CCC(F)(Cc5ccccn5)CC4)CC3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.51
▸ MAPT P10636 5/20 0.51
▸ HTT P42858 4/20 0.51
▸ SMN1; SMN2 Q16637 4/20 0.51
▸ TP53 P04637 4/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ MEN1 O00255 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ GAA P10253 2/20 0.50
▸ NPC1 O15118 1/20 0.49
▸ POLB P06746 1/20 0.48
▸ HTR1A P08908 2/20 0.46
▸ HTR7 P34969 2/20 0.46
▸ THRB P10828 1/20 0.46
▸ TSHR P16473 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL31546376 0.97 LMNA (0.49) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584958 0.89 MAPT (0.52) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667398 0.88 LMNA (0.55) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL31667543 0.86 LMNA (0.58) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL30584825 0.86 LMNA (0.52) LMNAMAPTHTTSMN1; SMN2TP53
Formic Acid SCHEMBL31546410 0.83 LMNA (0.56) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584805 0.80 LMNA (0.48) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584804 0.78 MEN1 (0.60) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584818 0.78 MEN1 (0.60) LMNAMAPTHTTSMN1; SMN2TP53
SCHEMBL30584775 0.78 LMNA (0.49) LMNAMAPTHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
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