SCHEMBL31667518

SCHEMBL31667518

O=C(NCOCN1CCC(Oc2ccccn2)CC1)N1CCN(c2nc(-c3ccc(OC(F)(F)F)cc3)no2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.45
▸ LMNA P02545 4/20 0.45
▸ TP53 P04637 4/20 0.45
▸ HTT P42858 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ THRB P10828 1/20 0.40
▸ CYP2C9 P11712 2/20 0.40
▸ EPHX2 P34913 2/20 0.40
▸ CYP2J2 P51589 2/20 0.40
▸ CHRM4 P08173 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ BCHE P06276 1/20 0.38
▸ ACHE P22303 1/20 0.38
▸ BACE1 P56817 1/20 0.38
▸ FAAH O00519 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667422 0.88 LMNA (0.45) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL31667494 0.82 LMNA (0.39) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL30584888 0.80 DRD2 (0.51) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL30584805 0.77 LMNA (0.48) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL31546384 0.76 LMNA (0.44) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL31546427 0.72 TSHR (0.50) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL30584857 0.70 MAPT (0.57) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL31667730 0.70 MAPT (0.55) MAPTLMNATP53HTTSMN1; SMN2
SCHEMBL25434754 0.69 MEN1 (0.56) MAPTLMNATP53HTTSMN1; SMN2
Formic Acid SCHEMBL30584798 0.68 MEN1 (0.56) MAPTLMNATP53HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
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