SCHEMBL31667494

SCHEMBL31667494

NC(=O)N1CCN(c2nc(-c3ccc(OC(F)(F)F)cc3)no2)CC1COCN1CCC(Oc2ccccn2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.39
▸ MAPT P10636 4/20 0.39
▸ TP53 P04637 2/20 0.39
▸ HTT P42858 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ RAB9A P51151 1/20 0.36
▸ DPP4 P27487 1/20 0.35
▸ DPP7 Q9UHL4 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ RET P07949 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CXCR3 P49682 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ SPHK2 Q9NRA0 1/20 0.33
▸ SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667518 0.82 MAPT (0.45) LMNAMAPTTP53HTTKDM4E
SCHEMBL31667422 0.70 LMNA (0.45) LMNAMAPTTP53HTTKDM4E
SCHEMBL31667730 0.69 MAPT (0.55) LMNAMAPTTP53HTTKDM4E
SCHEMBL31667497 0.68 MEN1 (0.52) LMNAMAPTTP53DPP4DPP7
SCHEMBL30584888 0.68 DRD2 (0.51) LMNAMAPTTP53HTTKDM4E
SCHEMBL30585023 0.66 LMNA (0.49) LMNAMAPTTP53HTTKDM4E
SCHEMBL25435130 0.65 FFAR4 (0.53) LMNAMAPTTP53THRBMEN1
Formic Acid SCHEMBL30584716 0.65 MEN1 (0.49) LMNAMAPTTP53DPP4DPP7
SCHEMBL30584805 0.65 LMNA (0.48) LMNAMAPTTP53HTTKDM4E
SCHEMBL25434754 0.64 MEN1 (0.56) LMNAMAPTTP53HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
Send feedback