Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31667305 | 0.89 | TOP2A (0.40) | TOP2ANPBWR1METALOX15L3MBTL1 | |
| SCHEMBL32686962 | 0.78 | UCHL1 (0.45) | TOP2ANPBWR1ALOX15L3MBTL1AKR1C3 | |
| SCHEMBL27840090 | 0.78 | TOP2A (0.48) | TOP2ANPBWR1ALOX15L3MBTL1MCHR1 | |
| SCHEMBL31285046 | 0.73 | TOP2A (0.48) | TOP2ANPBWR1METALOX15L3MBTL1 | |
| SCHEMBL18377688 | 0.71 | ALDH1A1 (0.54) | TOP2ANPBWR1ALOX15MCHR1CYP19A1 | |
| SCHEMBL30946374 | 0.71 | TOP2A (0.52) | TOP2ANPBWR1ALOX15MCHR1CYP19A1 | |
| SCHEMBL31284789 | 0.70 | TOP2A (0.48) | TOP2ANPBWR1METALOX15MCHR1 | |
| SCHEMBL13151306 | 0.69 | TOP2A (0.47) | TOP2ANPBWR1METALOX15L3MBTL1 | |
| SCHEMBL18367564 | 0.68 | TOP2A (0.49) | TOP2ANPBWR1METALOX15HSP90AA1 | |
| SCHEMBL4751007 | 0.68 | TOP2A (0.46) | TOP2ANPBWR1METALOX15MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| EP-4590674-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | TOP2A 3929/4885NPBWR1 128/4885MET 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.