Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31668711 | 0.81 | TRPV1 (0.65) | KMT2AGAANR3C1PGRNR3C2 | |
| SCHEMBL4502201 | 0.80 | L3MBTL1 (0.58) | KMT2AGAANR3C1PGRNR3C2 | |
| SCHEMBL4502200 | 0.80 | NR3C1 (0.49) | MAOBMAOANR3C1PGRNR3C2 | |
| SCHEMBL25582101 | 0.76 | POLB (0.51) | MAOBMAOAKMT2AGAANR3C1 | |
| SCHEMBL27698981 | 0.75 | KEAP1 (0.56) | KMT2ANR3C1PGRNR3C2AR | |
| SCHEMBL31668685 | 0.74 | MAPK1 (0.67) | MAOBMAOAKMT2AGAATRPV1 | |
| SCHEMBL6091339 | 0.73 | NR3C1 (0.57) | GAANR3C1PGRNR3C2AR | |
| SCHEMBL30026274 | 0.73 | PDPK1 (0.57) | GAANR3C1PGRNR3C2AR | |
| SCHEMBL31456523 | 0.73 | NR3C1 (0.57) | GAANR3C1PGRNR3C2AR | |
| SCHEMBL5497010 | 0.73 | PDPK1 (0.57) | GAANR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | SNCA, PARK7, SYNCRIP | MAOB 1849/4885MAOA 2552/4885KMT2A 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.