Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31625977 | 0.86 | ALDH1A1 (0.47) | OGG1ALDH1A1TSHRKIF11TGM2 | |
| SCHEMBL27266784 | 0.86 | ALDH1A1 (0.47) | OGG1ALDH1A1TSHRKIF11TGM2 | |
| SCHEMBL31671328 | 0.85 | OGG1 (0.41) | OGG1ALDH1A1TGM2MEN1KMT2A | |
| SCHEMBL29336758 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30750005 | 0.83 | OGG1 (0.40) | OGG1ALDH1A1TGM2MEN1KMT2A | |
| SCHEMBL8644325 | 0.82 | MEN1 (0.42) | ALDH1A1KIF11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31671261 | 0.80 | ALDH1A1 (0.36) | OGG1ALDH1A1TSHRKIF11TGM2 | |
| SCHEMBL31758886 | 0.80 | CA1 (0.39) | ALDH1A1KIF11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30750083 | 0.80 | KIF11 (0.38) | ALDH1A1KIF11MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31320998 | 0.79 | RIPK1 (0.44) | ALDH1A1KIF11MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250248975-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SCHRODINGER, LLC | 2025-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250248975-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCB1, PKD1 | OGG1 3809/4885ALDH1A1 3545/4885TSHR 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.