SCHEMBL31675871

SCHEMBL31675871

CNc1ncnc2c1ncn2[C@]1(C(=O)NC(=O)[C@@H](N)[C@@H](C)O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 3/20 0.41
▸ DOT1L Q8TEK3 4/20 0.40
▸ PRMT1 Q99873 1/20 0.40
▸ ADORA3 P0DMS8 4/20 0.40
▸ ADORA1 P30542 4/20 0.40
▸ ADORA2A P29274 1/20 0.38
▸ ADORA2B P29275 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275036 0.90 TARS1 (0.46) AHCYDOT1LADORA3ADORA1ADORA2A
SCHEMBL30862415 0.90 TARS1 (0.46) AHCYDOT1LADORA3ADORA1ADORA2A
SCHEMBL2185027 0.90 TARS1 (0.46) AHCYDOT1LADORA3ADORA1ADORA2A
SCHEMBL29435121 0.84 TARS1 (0.38) ADORA1
SCHEMBL28564130 0.84 TARS1 (0.38) ADORA1
SCHEMBL16987222 0.84 TARS1 (0.38) ADORA1
SCHEMBL29089525 0.80 TARS1 (0.39) ADORA1
SCHEMBL2033389 0.80 ADORA1 (0.38) ADORA3ADORA1ADORA2A
SCHEMBL21274225 0.80 TARS1 (0.37) ADORA3ADORA1ADORA2A
SCHEMBL30037173 0.80 ADORA1 (0.38) ADORA3ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12599679-B2 Circular RNA compositions ORNA THERAPEUTICS, INC. (US) 2026-04-14 — — US disclosed
US-20250262324-A1 Circular RNA Compositions ORNA THERAPEUTICS, INC. (US) 2025-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599679-B2 Circular RNA compositions BCL6, BCL9, BCL6B AHCY 3454/4885DOT1L 2399/4885PRMT1 332/4885
US-20250262324-A1 Circular RNA Compositions BCL9, IGF2BP1, BCL6 AHCY 4602/4885DOT1L 3028/4885PRMT1 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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