Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.45 |
| ▸ | ATXN2 | Q99700 | 6/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31677297 | 0.93 | ENPP2 (0.44) | ENPP2ATXN2ACACBSOS1TSHR | |
| SCHEMBL31677226 | 0.93 | ENPP2 (0.45) | ENPP2ATXN2ACACBSOS1TSHR | |
| SCHEMBL31677366 | 0.91 | SOS1 (0.48) | ENPP2ATXN2ACACBSOS1TSHR | |
| SCHEMBL31677315 | 0.91 | ENPP2 (0.45) | ENPP2ATXN2ACACBSOS1CYP2D6 | |
| SCHEMBL31677251 | 0.88 | SOS1 (0.44) | ENPP2ATXN2ACACBSOS1CYP2D6 | |
| SCHEMBL30966192 | 0.88 | TNKS (0.46) | SOS1TNKSCHRM2CHRM3ALDH1A1 | |
| SCHEMBL30816881 | 0.84 | GABRD (0.42) | SOS1TNKS | |
| SCHEMBL30816878 | 0.84 | GABRD (0.42) | SOS1TNKS | |
| SCHEMBL30864035 | 0.82 | CHRM2 (0.48) | TSHRCYP2D6CHRM2CHRM3ALDH1A1 | |
| SCHEMBL30816874 | 0.81 | CYP2D6 (0.51) | TSHRCYP2D6CHRM2CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |