Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045746 | 0.97 | LMNA (0.39) | LMNABLMPTPN1RECQLMEN1 | |
| SCHEMBL10045747 | 0.97 | LMNA (0.39) | LMNABLMPTPN1RECQLMEN1 | |
| SCHEMBL10045745 | 0.92 | TP53 (0.34) | LMNABLMRECQLCYP3A4TP53 | |
| SCHEMBL22106790 | 0.84 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL17792969 | 0.84 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL16072481 | 0.84 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL11820965 | 0.83 | TP53 (0.36) | RECQLTP53 | |
| Sulfuric Acid SCHEMBL14776390 | 0.81 | LMNA (0.45) | LMNABLMPTPN1RECQLMEN1 | |
| SCHEMBL10045744 | 0.81 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL12228507 | 0.81 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299308-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8232432-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-8044249-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| US-7994369-B2 | Specific polybranched polyaldehydes, polyalcohols, and surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885PTPN1 4053/4885 |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885PTPN1 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.