Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.60 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.60 |
| ▸ | ATIC | P31939 | 1/20 | 0.59 |
| ▸ | TCF4 | P15884 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662338 | 0.87 | KMT2A (0.65) | MAPK1LIMK1LIMK2TCF4CTNNB1 | |
| SCHEMBL4928453 | 0.86 | TCF4 (0.73) | MAPK1ATICTCF4CTNNB1ALDH1A1 | |
| SCHEMBL31681206 | 0.84 | TCF4 (0.76) | MAPK1LIMK1LIMK2TCF4CTNNB1 | |
| SCHEMBL3701951 | 0.83 | CA12 (0.71) | MAPK1TCF4CTNNB1ALDH1A1MAPT | |
| SCHEMBL5445300 | 0.82 | LMNA (0.66) | LIMK2ATICTCF4CTNNB1ALDH1A1 | |
| SCHEMBL4573407 | 0.82 | HPGD (0.74) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6318007 | 0.82 | HPGD (0.74) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL1592806 | 0.82 | LMNA (0.60) | MAPK1LIMK1LIMK2TCF4CTNNB1 | |
| SCHEMBL2240551 | 0.82 | HTR6 (0.73) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5452240 | 0.82 | TMPRSS6 (0.73) | ATICALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275539-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2025-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275539-A1 | APYRASE INHIBITORS | APEH, GBA3, PON1 | MAPK1 2652/4885LIMK1 4374/4885LIMK2 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.