SCHEMBL31683245

SCHEMBL31683245

O=C(Nc1ccc2nc(-c3ccc(F)c(F)c3)cn2c1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.59
SMN1; SMN2 Q16637 5/20 0.59
KDM4E B2RXH2 4/20 0.59
POLB P06746 3/20 0.59
LMNA P02545 2/20 0.59
GFER P55789 1/20 0.59
NPC1 O15118 5/20 0.56
ALDH1A1 P00352 5/20 0.55
HPGD P15428 3/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
CYP2C19 P33261 1/20 0.55
HTT P42858 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAPK1 P28482 2/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
MCHR1 Q99705 5/20 0.52
MAPT P10636 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26604713 1.00 RAB9A (0.59) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604699 0.91 KDM4E (0.53) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL31683201 0.91 KDM4E (0.53) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604695 0.90 KDM4E (0.52) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604710 0.90 MCHR1 (0.50) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604693 0.89 KDM4E (0.64) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL31683094 0.88 L3MBTL1 (0.54) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604709 0.88 L3MBTL1 (0.54) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL31683150 0.88 MAPT (0.57) RAB9ASMN1; SMN2KDM4EPOLBLMNA
SCHEMBL26604754 0.88 MAPT (0.57) RAB9ASMN1; SMN2KDM4EPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250283038-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250283038-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, IL2, IFNG RAB9A 1593/4885SMN1; SMN2 4812/4885KDM4E 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.