Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161531 | 0.93 | LTA4H (0.44) | L3MBTL1ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL3182451 | 0.88 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL3167777 | 0.88 | PPID (0.49) | L3MBTL1ALDH1A1MAPK1LTA4HMAPT | |
| SCHEMBL3177917 | 0.85 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1TDP1MAPK1CTSL | |
| SCHEMBL3175369 | 0.85 | GAA (0.47) | L3MBTL1ALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL3170802 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LTA4HMAPTMEN1KMT2A | |
| SCHEMBL2580034 | 0.82 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1TDP1MAPK1CTSL | |
| SCHEMBL3175029 | 0.82 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL3171210 | 0.81 | SYK (0.42) | L3MBTL1ALDH1A1TDP1MAPK1MAPT | |
| SCHEMBL3178284 | 0.81 | TSHR (0.48) | L3MBTL1ALDH1A1TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |