SCHEMBL31685377

SCHEMBL31685377

CN1C(=O)C=CN([C@H]2C[C@H](OP(=O)(O)O)[C@@H](CO)O2)C1N

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ P2RY1 P47900 1/20 0.34
▸ RNASE1 P07998 1/20 0.32
▸ TK1 P04183 1/20 0.32
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685730 0.81 LMNA (0.44) TK1
SCHEMBL31685487 0.79 TYMS (0.46) —
SCHEMBL31685513 0.77 ADORA1 (0.42) —
SCHEMBL31685300 0.73 P2RY1 (0.41) P2RY1
SCHEMBL31685646 0.72 TK1 (0.44) P2RY1RNASE1TK1
SCHEMBL31685660 0.70 POLB (0.41) P2RY1RNASE1TK1POLB
SCHEMBL31685710 0.69 LMNA (0.42) POLB
SCHEMBL10331938 0.69 RNASE1 (0.45) P2RY1RNASE1TK1POLB
SCHEMBL6517103 0.69 RNASE1 (0.45) P2RY1RNASE1TK1POLB
SCHEMBL31685407 0.69 POLB (0.39) P2RY1RNASE1TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 P2RY1 2249/4885RNASE1 3/4885TK1 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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