Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703621 | 0.85 | DRD2 (0.54) | DRD2SMN1; SMN2SIGMAR1TDP1CACNA1H | |
| SCHEMBL24619896 | 0.83 | DRD2 (0.54) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL22699069 | 0.83 | DRD2 (0.54) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL18947871 | 0.83 | DRD2 (0.54) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL8254760 | 0.82 | DRD2 (0.64) | DRD2SMN1; SMN2SIGMAR1TDP1CACNA1H | |
| SCHEMBL6700 | 0.82 | DRD2 (0.53) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL24922242 | 0.80 | DRD2 (0.51) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL17623586 | 0.79 | TDP1 (0.48) | DRD2SMN1; SMN2TDP1GNAI3GNAO1 | |
| SCHEMBL25031746 | 0.79 | DRD2 (0.55) | DRD2SIGMAR1TDP1CACNA1HMEN1 | |
| SCHEMBL21815267 | 0.79 | DRD2 (0.50) | DRD2SIGMAR1TDP1CACNA1HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620949-A1 | ACKR3 MODULATORS FOR CARDIOVASCULAR OR ANTIPLATELET THERAPY | Eberhard Karls Universität Tübingen (Medizinische Fakultät) (DE) | 2025-09-24 | — | — | EP | disclosed |