Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146247 | 0.84 | KDM4E (0.42) | TSHRALDH1A1ADORA2AADORA1ADORA2B | |
| SCHEMBL21731189 | 0.79 | ADORA2A (0.68) | EGLN2ADORA2AADORA1ADORA2B | |
| SCHEMBL31722875 | 0.75 | CYP1A2 (0.43) | EGLN2CYP1A2CYP3A4USP2TSHR | |
| SCHEMBL21731117 | 0.71 | ADORA2A (0.44) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21731050 | 0.70 | ADORA2A (0.64) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21731135 | 0.70 | ADORA2A (0.65) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6010018 | 0.69 | ADORA2A (0.38) | EGLN2TSHRALDH1A1ADORA2AADORA1 | |
| SCHEMBL29781584 | 0.68 | ADORA2A (0.61) | ADORA2AADORA1ADORA2B | |
| SCHEMBL24129977 | 0.68 | ADORA2A (0.54) | ADORA2AADORA2B | |
| SCHEMBL10430692 | 0.68 | XDH (0.42) | EGLN2ALDH1A1ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883575-B1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC (US) | 2025-10-08 | — | — | EP | disclosed |