Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777172 | 0.82 | TP53 (0.33) | TP53EPHX2 | |
| SCHEMBL15552284 | 0.79 | KCNA5 (0.36) | IRAK4 | |
| SCHEMBL15552282 | 0.79 | KCNA5 (0.36) | IRAK4 | |
| SCHEMBL21693823 | 0.74 | MCOLN3 (0.31) | — | |
| SCHEMBL3219786 | 0.74 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL477548 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL26919921 | 0.73 | MEP1B (0.34) | EPHX2 | |
| SCHEMBL21192385 | 0.73 | MPL (0.33) | TP53EPHX2 | |
| SCHEMBL25340461 | 0.72 | MPL (0.32) | EPHX2 | |
| SCHEMBL20573229 | 0.72 | EPHX2 (0.38) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313569-A1 | Pharmaceutical Compounds And Compositions As Modulators Of MAS-Related G-Protein Receptor X2 | ENANTA PHARMACEUTICALS, INC. | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313569-A1 | Pharmaceutical Compounds And Compositions As Modulators Of MAS-Related G-Protein Receptor X2 | MRGPRX2, MRGPRX1, MRGPRX4 | TP53 2677/4885EPHX2 537/4885IRAK4 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.