SCHEMBL31701191

SCHEMBL31701191

Cc1cc(C(=O)O)c(C)cc1/N=N/c1cc(C)c(C(=O)O)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 2/20 0.47
MAPK1 P28482 2/20 0.47
PSMD14 O00487 1/20 0.47
HSP90AA1 P07900 1/20 0.47
MMP2 P08253 1/20 0.47
THRB P10828 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
ALDH1A1 P00352 4/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31701751 0.86 PHLPP2 (0.50) MAPTMEN1KMT2ANPSR1GAA
SCHEMBL70135 0.83 KDM4E (0.54) MEN1KMT2AGAAMAPK1TDP1
Hydrochloric Acid SCHEMBL4352648 0.81 KDM4E (0.52) MEN1KMT2AGAAMAPK1TDP1
Ethylene SCHEMBL6034661 0.79 KDM4E (0.50) MEN1KMT2AGAAMAPK1TDP1
SCHEMBL2400964 0.79 KDM4E (0.50) MEN1KMT2AGAAMAPK1TDP1
SCHEMBL238021 0.79 KDM4E (0.50) MEN1KMT2AGAAMAPK1TDP1
SCHEMBL29350418 0.79 KDM4E (0.50) MEN1KMT2AGAAMAPK1TDP1
SCHEMBL69934 0.76 KDM4E (0.50) MEN1KMT2AGAATDP1KDM4E
Ethylene Glycol SCHEMBL27658105 0.75 KDM4E (0.47) MEN1KMT2AGAAMAPK1TDP1
SCHEMBL20172100 0.74 KDM4E (0.42) MEN1KMT2AGAAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320236-A1 METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF USE CONWAY DAVID JONATHAN (US) 2025-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320236-A1 METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF USE OGFOD1, OCIAD1, MLYCD MAPT 2001/4885MEN1 3348/4885KMT2A 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.