Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | BLVRB | P30043 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31702340 | 0.88 | KMT2A (0.57) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL31701191 | 0.86 | MAPT (0.47) | PHLPP2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL20741612 | 0.83 | TDP1 (0.58) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL31701516 | 0.81 | TRPA1 (0.58) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL12589872 | 0.75 | RXRB (0.45) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL3399265 | 0.75 | CYP3A4 (0.53) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL27671132 | 0.72 | PHLPP2 (0.67) | PHLPP2MEN1KMT2AHTTPDE4A | |
| SCHEMBL13758628 | 0.72 | PHLPP2 (0.58) | PHLPP2MEN1KMT2AHTTMAPT | |
| SCHEMBL70135 | 0.72 | KDM4E (0.54) | MEN1KMT2AGAATDP1MAPK1 | |
| SCHEMBL21067788 | 0.71 | KMT2A (0.69) | PHLPP2MEN1KMT2AHTTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320236-A1 | METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF USE | CONWAY DAVID JONATHAN (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320236-A1 | METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF USE | OGFOD1, OCIAD1, MLYCD | PHLPP2 3724/4885MEN1 3348/4885KMT2A 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.