SCHEMBL317019

SCHEMBL317019

CC1=Nc2ccc(Br)cc2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTR2B P41595 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
BACE1 P56817 4/20 0.32
APP P05067 3/20 0.32
CCNE2 O96020 1/20 0.31
CDK2 P24941 1/20 0.31
CCND3 P30281 1/20 0.31
CDK6 Q00534 1/20 0.31
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184823 0.85 MEN1 (0.35) MEN1KMT2AHTR2BSIGMAR1CASP3
SCHEMBL15066789 0.81 MEN1 (0.37) MEN1KMT2ABACE1ALDH1A1
SCHEMBL101511 0.80 TDP1 (0.41) MEN1KMT2ABACE1CCNE2CDK2
SCHEMBL38660687 0.80 TDP1 (0.41) MEN1KMT2ABACE1CCNE2CDK2
SCHEMBL31142510 0.77 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL661200 0.77 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL3418732 0.77 MEN1 (0.39) MEN1KMT2ACCNE2CDK2CCND3
SCHEMBL665154 0.77 MEN1 (0.39) MEN1KMT2ABACE1CCNE2CDK2
SCHEMBL10035871 0.77 MEN1 (0.39) MEN1KMT2ACCNE2CDK2CCND3
SCHEMBL1714750 0.77 MEN1 (0.39) MEN1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126048-A Preparation and application methods of cuporphyrin cyanine nano particles with switchable photodynamic and photothermal effects and chemical dynamic effects 北京化工大学 2024-06-04 CN claimed
CN-111606915-B Preparation method of spiropyran photochromic material 浙大宁波理工学院 2021-06-15 CN claimed
CN-111606915-A Preparation method of spiropyran photochromic material 浙大宁波理工学院 2020-09-01 CN claimed
EP-4171957-B1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR ECO3 BV (BE) 2025-02-12 EP disclosed
CN-118290959-A Meso-position substituted cyanine dye of anthraquinone and anthracene compounds, and preparation method and application thereof 大连理工大学 2024-07-05 CN disclosed
CN-118126048-A Preparation and application methods of cuporphyrin cyanine nano particles with switchable photodynamic and photothermal effects and chemical dynamic effects 北京化工大学 2024-06-04 CN disclosed
CN-118001946-A Spiropyran polymer membrane material for gas separation and preparation method and application thereof 中南大学 2024-05-10 CN disclosed
CN-117986182-A AIE heptamethine cyanine photosensitizer for bimodal imaging and diagnosis and treatment as well as preparation method and application thereof 河南大学 2024-05-07 CN disclosed
CN-115322121-B Organic hole transport material and perovskite solar cell prepared from same 华中科技大学鄂州工业技术研究院 2024-02-09 CN disclosed
CN-117304176-A Enzyme-activated prodrug compound and preparation method and application thereof 大连理工大学 2023-12-29 CN disclosed
CN-116854621-A Photosensitizer taking pentamethine cyanine dye as matrix, and synthesis method and application thereof 大连理工大学 2023-10-10 CN disclosed
WO-2002085854-A1 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1211294-A1 Improved process and method for the preparation of asymmetric monofunctionalised indocyanine labelling reagents and obtained compounds Innosense S.r.l. (IT) 2002-06-05 EP disclosed
US-20020065421-A1 Process and method for the preparation of asymmetric monfunctionalised indocyanine labelling reagents and obtained compounds VISEN MEDICAL, INC. 2002-05-30 US disclosed
EP-1209205-A1 Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds Innosense S.r.l. (IT) 2002-05-29 EP disclosed
US-6004719-A ACID-GENERATING LAYER OR PHASE COMPRISING A MIXTURE OF A SUPERACID PRECURSOR, A SENSITIZING DYE AND A SECONDARY ACID GENERATOR, AND A COLOR-CHANGE LAYER OR PHASE COMPRISING AN IMAGE DYE. POLAROID CORPORATION (US) 1999-12-21 US disclosed
EP-0223606-B1 Photothermographic materials MINNESOTA MINING & MFG (US) 1993-12-15 EP disclosed
US-4756999-A Imine containing antifogging agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-07-12 US disclosed
EP-0223606-A2 Photothermographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-27 EP disclosed
US-4110070-A QUATERNIZING INDOLENINE METHINE COMPOUND ON FIBERS TO FORM CATIONIC DYE HODOGAYA CHEMICAL CO., LTD. (JP) 1978-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065421-A1 Process and method for the preparation of asymmetric monfunctionalised indocyanine labelling reagents and obtained compounds IDO1, IDO2, AADAT MEN1 482/4885KMT2A 420/4885HTR2B 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.