SCHEMBL665154

SCHEMBL665154

CC1=Nc2ccc(N)cc2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CASP6 P55212 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CASP1 P29466 2/20 0.34
EHMT2 Q96KQ7 1/20 0.34
CCNE2 O96020 1/20 0.33
CDK2 P24941 1/20 0.33
CCND3 P30281 1/20 0.33
CDK6 Q00534 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
PDE10A Q9Y233 1/20 0.32
BACE1 P56817 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PLAU P00749 1/20 0.31
CASP3 P42574 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101511 0.80 TDP1 (0.41) MEN1KMT2AKDM4ELMNAALDH1A1
SCHEMBL38660687 0.80 TDP1 (0.41) MEN1KMT2AKDM4ELMNAALDH1A1
SCHEMBL1714750 0.77 MEN1 (0.39) MEN1KMT2ALMNACYP3A4SMN1; SMN2
SCHEMBL661200 0.77 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL3418732 0.77 MEN1 (0.39) MEN1KMT2AALDH1A1CCNE2CDK2
SCHEMBL10035871 0.77 MEN1 (0.39) MEN1KMT2ACCNE2CDK2CCND3
SCHEMBL317019 0.77 MEN1 (0.39) MEN1KMT2ALMNAALDH1A1CCNE2
SCHEMBL31142510 0.77 MEN1 (0.39) MEN1KMT2ACASP3RAB9AATM
SCHEMBL2008332 0.77 MEN1 (0.36) MEN1KMT2AALDH1A1CYP3A4SMN1; SMN2
SCHEMBL5851896 0.77 CCNE2 (0.38) MEN1KMT2AKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044539-A2 NIR-LIGHT ACTIVATABLE NANOGEL DELIVERY SYSTEM THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-02-29 WO disclosed
WO-2024044539-A2 NIR-LIGHT ACTIVATABLE NANOGEL DELIVERY SYSTEM THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-02-29 WO disclosed
WO-2021101145-A1 QUENCHER AND USES THEREOF 에스에프씨 주식회사 2021-05-27 WO disclosed
CN-106281306-B The near-infrared fluorescent group of reversible instruction physiological phenomenon environment 复旦大学 2019-08-09 CN disclosed
EP-1981846-B1 MARKERS, METHOD FOR MANUFACTURING THEM AND THEIR APPLICATIONS LABORATOIRES SYNTH-INNOVE (FR) 2017-11-01 EP disclosed
EP-1981846-B1 MARKERS, METHOD FOR MANUFACTURING THEM AND THEIR APPLICATIONS LABORATOIRES SYNTH-INNOVE (FR) 2017-11-01 EP disclosed
CN-106281306-A The near-infrared fluorescent group of reversible instruction physiological phenomenon environment 复旦大学 2017-01-04 CN disclosed
EP-1954763-B1 CYANINE DYES AND METHODS FOR DETECTING A TARGET USING SAID DYES DAKO DENMARK AS (DK) 2016-11-16 EP disclosed
US-9040722-B2 Photoelectric conversion device and photoelectric conversion device dye, and compound ADEKA CORPORATION (JP) 2015-05-26 US disclosed
US-9040722-B2 Photoelectric conversion device and photoelectric conversion device dye, and compound ADEKA CORPORATION (JP) 2015-05-26 US disclosed
WO-2005088308-A2 FLUORESCENT SIGNAL EMITTING LIVE CELL BIOSENSOR MOLECULES AND DYES FOR DETECTION AND QUANTIFICATION OF PROTEIN ACTIVITIES THE SCRIPPS RESEARCH INSTITUTE (US) 2005-09-22 WO disclosed
EP-0189188-B1 OPTICAL RECORDING MEDIUM SONY CORPORATION (JP) 1992-01-02 EP disclosed
US-4753867-A INDOLINOSPIROBENZOTHIOPYRAN COMPOUND SONY CORPORATION (JP) 1988-06-28 US disclosed
EP-0115201-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING PHOTOCHROMIC COMPOUNDS SONY CORPORATION (JP) 1988-03-02 EP disclosed
EP-0189188-A2 Optical recording medium SONY CORPORATION (JP) 1986-07-30 EP disclosed
US-4565779-A Photochromic compounds and photosensitive compositions containing the compounds SONY CORPORATION (JP) 1986-01-21 US disclosed
EP-0115201-A2 Photosensitive compositions containing photochromic compounds SONY CORPORATION (JP) 1984-08-08 EP disclosed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 US disclosed