Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163028 | 0.90 | KMT2A (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3164802 | 0.86 | L3MBTL1 (0.52) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3174225 | 0.86 | TP53 (0.43) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3170639 | 0.86 | KMT2A (0.48) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3171330 | 0.85 | CA1 (0.48) | MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3162285 | 0.83 | HRH4 (0.44) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3169166 | 0.82 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3171377 | 0.82 | ALDH1A1 (0.56) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3171389 | 0.82 | ALDH1A1 (0.56) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3166477 | 0.81 | MAPT (0.61) | L3MBTL1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465631-B1 | PYRIMIDINE A2B SELECTIVE ANTAGONIST COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2010-02-24 | — | — | EP | disclosed |