SCHEMBL31703809

SCHEMBL31703809

NC1=NCc2nccnc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633795 0.67 TSHR (0.48) TSHR
SCHEMBL12856206 0.62
SCHEMBL14380284 0.58 ALDH1A1 (0.36)
SCHEMBL19239761 0.57
SCHEMBL5152107 0.54 S100A4 (0.33)
SCHEMBL15386163 0.54 LMNA (0.32)
SCHEMBL11839427 0.54
SCHEMBL5154571 0.54 ALDH1A1 (0.33)
SCHEMBL29985108 0.53
SCHEMBL1024624 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215303-A1 SULFONAMIDES, COMPOSITIONS COMPRISING SAID SULFONAMIDES, METHODS FOR THE PREPARATION OF SAID SULFONAMIDES, AND SAID SULFONAMIDES FOR USE AS MEDICAMENT AND IN A METHOD FOR THE TREATMENT OR PREVENTION OF AN OCULAR DISEASE OR CONDITION, OR IDIOPATHIC INTRACRANIAL HYPERTENSION ITÄ-SUOMEN YLIOPISTO (FI) 2025-10-16 WO disclosed
WO-2025215286-A1 SULFONAMIDES, COMPOSITIONS COMPRISING SAID SULFONAMIDES, METHODS FOR THE PREPARATION OF SAID SULFONAMIDES, AND SAID SULFONAMIDES FOR USE AS MEDICAMENT AND IN A METHOD FOR THE TREATMENT OR PREVENTION OF AN OCULAR DISEASE OR CONDITION, OR IDIOPATHIC INTRACRANIAL HYPERTENSION ITÄ-SUOMEN YLIOPISTO (FI) 2025-10-16 WO disclosed