Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 3/20 | 0.34 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16550314 | 0.71 | CYP11B2 (0.36) | TSHRTDP2NSD2PAX8TDP1 | |
| SCHEMBL28824497 | 0.71 | TRIM24 (0.36) | TDP2NSD2PAX8TDP1ABL1 | |
| SCHEMBL802342 | 0.71 | PDK2 (0.36) | TSHRTDP2NSD2PAX8TDP1 | |
| SCHEMBL22579802 | 0.67 | TDP1 (0.42) | TSHRTDP2NSD2PAX8TDP1 | |
| SCHEMBL585349 | 0.67 | TDP1 (0.42) | TSHRTDP2NSD2PAX8TDP1 | |
| SCHEMBL1194687 | 0.67 | TSHR (0.95) | TSHRNOS2NOS3KDM4ELMNA | |
| SCHEMBL31703623 | 0.67 | TSHR (0.95) | TSHRNOS2NOS3KDM4ELMNA | |
| SCHEMBL31703946 | 0.67 | TSHR (0.48) | TSHRNOS2NOS3TDP2NSD2 | |
| SCHEMBL3360704 | 0.67 | TSHR (0.48) | TSHRNOS2NOS3TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL4092945 | 0.65 | TSHR (1.00) | TSHRNOS2NOS3KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |