SCHEMBL3170437

SCHEMBL3170437

O=C(O)[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@H](O)[C@H](O)CO

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.41
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
PGD P52209 1/20 0.37
LMNA P02545 2/20 0.35
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
OR51E2 Q9H255 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2422500 0.86 PDE4A (0.48) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL7076428 0.85 PDE4A (0.32) PDE4AUSP2SLCO1B1LMNAL3MBTL1
SCHEMBL7764499 0.84 PDE4A (0.52) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL30924493 0.83 PGD (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL19514770 0.81 LMNA (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL27772430 0.81 LMNA (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL9456987 0.81 LMNA (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL7695502 0.81 LMNA (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL17555601 0.81 LMNA (0.42) PDE4AUSP2SLCO1B1PGDLMNA
SCHEMBL177758 0.77 MPI (0.46) PDE4ALMNAL3MBTL1TDP1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004235-B1 COMPOSITION FOR COSMETIC OR PHARMACEUTICAL-DERMATOLOGICAL USE PHARMALAND S A (SM) 2010-03-24 EP disclosed
US-20090098226-A1 COMPOSITION FOR COSMETIC OR PHARMACEUTICAL-DERMATOLOGICAL USE SCHARPER S.P.A. (IT) 2009-04-16 US disclosed
EP-2004235-A2 COMPOSITION FOR COSMETIC OR PHARMACEUTICAL-DERMATOLOGICAL USE Scharper S.p.A. (IT) 2008-12-24 EP disclosed
WO-2007105071-A2 COMPOSITION FOR COSMETIC OR PHARMACEUTICAL-DERMATOLOGICAL USE SCHARPER S.P.A. (IT) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098226-A1 COMPOSITION FOR COSMETIC OR PHARMACEUTICAL-DERMATOLOGICAL USE CUTA, DSG1, PHOSPHO1 PDE4A 3351/4885USP2 2518/4885SLCO1B1 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.