SCHEMBL317047

SCHEMBL317047

[C]1CCCc2cc3c(cc21)CCCC3

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42412 0.74 MEN1 (0.36) MEN1KMT2ATSHR
SCHEMBL577943 0.73 CYP3A4 (0.45) KDM4EALDH1A1GAAMAPTTSHR
SCHEMBL1760720 0.72 TSHR (0.50) CDC25BKDM4EMEN1ALDH1A1GAA
SCHEMBL1779152 0.70 CYP4F2 (0.36)
SCHEMBL2879792 0.70 NPC1 (0.38) MEN1ALDH1A1GAAMAPTKMT2A
SCHEMBL7574903 0.70 PNMT (0.36) L3MBTL1
SCHEMBL3106114 0.70 MAOA (0.43) ALDH1A1MAPT
SCHEMBL3540397 0.70 KDM1A (0.38) KMT2A
SCHEMBL5713757 0.70 PNMT (0.36) L3MBTL1
SCHEMBL25202453 0.69 CDC25B (0.48) CDC25BKDM4EMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP claimed
CN-113201084-A Molecular weight control of polyolefins using halogenated bisphenylphenoxy catalysts 陶氏环球技术有限责任公司 2021-08-03 CN claimed
CN-106687486-B Bis-biphenylphenoxy catalysts for polymerization of low molecular weight ethylene-based polymers 陶氏环球技术有限责任公司 2021-03-19 CN claimed
EP-3578578-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS Dow Global Technologies Llc (US) 2019-12-11 EP claimed
EP-2797963-B1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-03 EP claimed
US-9975975-B2 Bis-biphenylphenoxy catalysts for polymerization of low molecular weight ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-22 US claimed
US-20170137550-A1 BIS-BIPHENYLPHENOXY CATALYSTS FOR POLYMERIZATION OF LOW MOLECULAR WEIGHT ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-05-18 US claimed
US-9605098-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-28 US claimed
US-9601231-B2 Hyperbranched olefin oil-based dielectric fluid DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-21 US claimed
US-9522855-B2 Process for producing low molecular weight ethylene- and alpha-olefin-based materials DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-20 US claimed
WO-2014210333-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO claimed
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-04 US claimed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US claimed
EP-2797962-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS Dow Global Technologies LLC (US) 2014-11-05 EP claimed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP claimed
WO-2013101375-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO claimed
EP-2491062-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2012-08-29 EP claimed
WO-2011146044-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO claimed
WO-2011146291-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-24 WO claimed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS EEF1D, EPN1, ELOC CDC25B 4360/4885KDM4E 2288/4885MEN1 959/4885
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 CDC25B 4524/4885KDM4E 3753/4885MEN1 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.