Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705168 | 0.89 | ATM (0.43) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL31706677 | 0.84 | TDP1 (0.52) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| Lithium Ion SCHEMBL31706878 | 0.82 | TDP1 (0.50) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| Lithium Ion SCHEMBL31704582 | 0.82 | TDP1 (0.50) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3939071 | 0.81 | ATM (0.53) | MAPTKMT2AMEN1ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL3327647 | 0.81 | ATM (0.47) | MAPTKMT2AALDH1A1ATMCYP11B1 | |
| SCHEMBL23572659 | 0.80 | GPR119 (0.48) | MAPTKMT2AMEN1ALDH1A1ATM | |
| SCHEMBL31706262 | 0.80 | ATM (0.46) | KMT2AMEN1ALDH1A1ATMGAA | |
| SCHEMBL20604746 | 0.79 | CHRNB2 (0.61) | ALDH1A1ATMCYP11B1CYP11B2CHRNB2 | |
| SCHEMBL664858 | 0.79 | ATM (0.50) | MAPTKMT2AMEN1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |