Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705602 | 0.87 | NAMPT (0.48) | TDP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL29420013 | 0.86 | CHRNB2 (0.51) | KMT2AALDH1A1MEN1CHRNB2CHRNA4 | |
| SCHEMBL20187819 | 0.86 | CHRNB2 (0.51) | KMT2AALDH1A1MEN1CHRNB2CHRNA4 | |
| Lithium Ion SCHEMBL31706878 | 0.86 | TDP1 (0.50) | TDP1MAPTKMT2AALDH1A1MEN1 | |
| Lithium Ion SCHEMBL31704582 | 0.86 | TDP1 (0.50) | TDP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL31705087 | 0.84 | TDP1 (0.48) | TDP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL20206172 | 0.82 | CHRNB2 (0.63) | KMT2AALDH1A1MEN1CHRNB2CHRNA4 | |
| SCHEMBL23610380 | 0.82 | CHRNB2 (0.55) | MAPTKMT2AALDH1A1MEN1CHRNB2 | |
| SCHEMBL29420017 | 0.82 | CHRNB2 (0.55) | MAPTKMT2AALDH1A1MEN1CHRNB2 | |
| SCHEMBL5593185 | 0.80 | ALDH1A1 (0.57) | MAPTKMT2AALDH1A1MEN1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |