SCHEMBL3170606

SCHEMBL3170606

Cc1ccccc1P(C1CCCC1)C1CCCC1.[Pd]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
LMNA P02545 1/20 0.34
SIGMAR1 Q99720 3/20 0.33
P2RX7 Q99572 3/20 0.33
HTR2C P28335 2/20 0.32
SLC18A3 Q16572 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
ROCK2 O75116 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3165316 0.98 NPC1 (0.37) TSHRACHENPC1RAB9ALMNA
SCHEMBL3185842 0.98 TSHR (0.36) TSHRACHENPC1RAB9ALMNA
SCHEMBL301552 0.96 NPC1 (0.38) TSHRACHENPC1RAB9ALMNA
SCHEMBL15659453 0.90 ACHE (0.39) TSHRACHENPC1RAB9ALMNA
SCHEMBL1314189 0.83 ROCK2 (0.33) ROCK2
SCHEMBL197441 0.82 S1PR1 (0.36) ACHENPC1RAB9ASIGMAR1P2RX7
SCHEMBL29391022 0.82 S1PR1 (0.36) ACHENPC1RAB9ASIGMAR1P2RX7
SCHEMBL29350531 0.82 S1PR1 (0.36) ACHENPC1RAB9ASIGMAR1P2RX7
SCHEMBL205843 0.81 ROCK2 (0.38) TSHRNPC1RAB9ALMNASIGMAR1
SCHEMBL15660440 0.81 GAA (0.40) TSHRNPC1RAB9ALMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084563-B2 Cyclic olefin addition copolymer, process for production thereof, and retardation film obtained from the copolymer JSR CORPORATION (JP) 2011-12-27 US disclosed
US-20100021707-A1 CYCLIC OLEFIN ADDITION COPOLYMER, METHOD FOR PRODUCING THE SAME, AND RETARDATION FILM OBTAINED FROM THE COPOLYMER JSR CORPORATION (JP) 2010-01-28 US disclosed
EP-2039708-A1 CYCLIC OLEFIN ADDITION COPOLYMER, METHOD FOR PRODUCING THE SAME, AND RETARDATION FILM OBTAINED FROM THE COPOLYMER JSR Corporation (JP) 2009-03-25 EP disclosed
US-7482412-B2 Process for manufacturing cycloolefin addition polymer JSR CORPORATION (JP) 2009-01-27 US disclosed
US-20080085979-A1 PROCESS FOR MANUFACTURING CYCLOOLEFIN ADDITION POLYMER JSR CORPORATION (JP) 2008-04-10 US disclosed