Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963331 | 0.98 | ROCK2 (0.38) | ROCK2ALOX12EPHX1SIGMAR1GAA | |
| Perchlorate SCHEMBL9676819 | 0.92 | ROCK2 (0.35) | ROCK2ALOX12EPHX1SIGMAR1GAA | |
| SCHEMBL8960743 | 0.91 | ROCK2 (0.34) | ROCK2ALOX12EPHX1 | |
| Perchlorate SCHEMBL9676816 | 0.89 | ROCK2 (0.33) | ROCK2ALOX12EPHX1SIGMAR1GAA | |
| SCHEMBL3929841 | 0.89 | SIGMAR1 (0.35) | ROCK2ALOX12EPHX1SIGMAR1LMNA | |
| SCHEMBL12015428 | 0.89 | HPGD (0.40) | ROCK2ALOX12EPHX1SIGMAR1LMNA | |
| SCHEMBL29584884 | 0.89 | SIGMAR1 (0.35) | ROCK2ALOX12EPHX1SIGMAR1LMNA | |
| SCHEMBL8960858 | 0.88 | ROCK2 (0.38) | ROCK2SIGMAR1LMNAGRIN2DGRIN3B | |
| SCHEMBL8961009 | 0.87 | ROCK2 (0.34) | ROCK2ALDH1A1TSHR | |
| SCHEMBL645784 | 0.86 | DDB1 (0.38) | ROCK2ALOX12EPHX1SIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840116-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2012-10-03 | — | — | EP | claimed |
| US-7781609-B2 | Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | claimed |
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | NISSAN CHEMICAL INDUSTRIAL, LTD. (JP) | 2008-06-12 | — | — | US | claimed |
| EP-1840116-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2007-10-03 | — | — | EP | claimed |
| EP-0408340-B1 | Ruthenium-optically active phoshine complex useful as catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 1996-01-24 | — | — | EP | claimed |
| EP-0408338-B1 | Catalytic production of carboxylic acids and esters thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-09-27 | — | — | EP | claimed |
| US-5087728-A | Hydrogenating unsaturated compound using rhodium or ruthenium complex catalyst with specific diphosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-02-11 | — | — | US | claimed |
| US-5021593-A | Used as hydrogenation, silylation or isomerization catalysts | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1991-06-04 | — | — | US | claimed |
| EP-0408340-A2 | Ruthenium-optically active phoshine complex useful as catalyst | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | claimed |
| EP-0408338-A2 | Catalytic production of carboxylic acids and esters thereof | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | claimed |
| JP-3275691-A | — | — | None | — | — | JP | disclosed |
| US-12129249-B2 | Method for producing optically active compound | DAY ONE BIOPHARMACEUTICALS, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| EP-4406609-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | Day One Biopharmaceuticals, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| CN-118005619-A | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-110753689-B | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2024-01-26 | — | — | CN | disclosed |
| US-5021593-A | Used as hydrogenation, silylation or isomerization catalysts | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0408340-A2 | Ruthenium-optically active phoshine complex useful as catalyst | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0408338-A2 | Catalytic production of carboxylic acids and esters thereof | Takasago International Corporation (JP) | 1991-01-16 | — | — | EP | disclosed |
| US-4857648-A | Isoquinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0315886-A2 | Isoquinoline derivatives, their manufacture and use | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | HCAR2, HCAR1, ALDH7A1 | ROCK2 2784/4885ALOX12 181/4885EPHX1 1222/4885 |
| US-12129249-B2 | Method for producing optically active compound | DHPS, QDPR, SPR | ROCK2 978/4885ALOX12 1843/4885EPHX1 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.