Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606965 | 0.93 | FAAH (0.46) | FAAHMEN1MAPK1KMT2ANOD1 | |
| SCHEMBL607464 | 0.84 | L3MBTL1 (0.46) | FAAHMEN1MAPK1KMT2A | |
| SCHEMBL608030 | 0.84 | FAAH (0.47) | FAAHMEN1MAPK1KMT2ANOD1 | |
| SCHEMBL606723 | 0.83 | EPHX1 (0.47) | ASAH1 | |
| SCHEMBL26032021 | 0.82 | FAAH (0.54) | FAAHMEN1MAPK1KMT2ANOD1 | |
| SCHEMBL607103 | 0.81 | ASAH2 (0.45) | ASAH2 | |
| SCHEMBL607375 | 0.81 | NOD1 (0.47) | FAAHMEN1MAPK1KMT2ANOD1 | |
| SCHEMBL607096 | 0.80 | LMNA (0.46) | FAAHMEN1KMT2A | |
| SCHEMBL20272895 | 0.79 | FAAH (0.61) | FAAHMEN1MAPK1KMT2ANOD1 | |
| SCHEMBL609022 | 0.79 | FAAH (0.50) | FAAHMEN1MAPK1KMT2ANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | claimed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | claimed |