Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708108 | 0.84 | PDE2A (0.51) | PDE2AALDH1A1CYP1A2KDM4E | |
| SCHEMBL31708020 | 0.84 | HRH4 (0.33) | PDE2AHRH4HSD17B10 | |
| SCHEMBL10220211 | 0.77 | HRH4 (0.50) | LMNATDP1ALDH1A1CYP3A4HTR6 | |
| SCHEMBL25217067 | 0.75 | CYP2C19 (0.35) | PDE2AALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL31708045 | 0.75 | CYP2C19 (0.35) | PDE2AALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL31708110 | 0.74 | FFAR1 (0.33) | — | |
| SCHEMBL15218853 | 0.73 | LMNA (0.45) | LMNATDP1ALDH1A1CYP3A4HTR6 | |
| SCHEMBL25239087 | 0.72 | PDE2A (0.33) | TDP1PDE2ASMN1; SMN2 | |
| SCHEMBL439716 | 0.70 | LMNA (0.59) | LMNATDP1PDE2AALDH1A1CYP3A4 | |
| SCHEMBL31708038 | 0.66 | HSP90AA1 (0.32) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143179-B1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-22 | — | — | EP | disclosed |