Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709213 | 0.82 | KDM4E (0.58) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL27142753 | 0.82 | KDM4E (0.63) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL31709200 | 0.82 | ATAD2 (0.48) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL27140915 | 0.81 | KDM4E (0.61) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL31464148 | 0.80 | MEN1 (0.67) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL3602510 | 0.80 | FAAH (0.69) | KDM4EALOX15ALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL27137135 | 0.80 | MEN1 (0.66) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL27149658 | 0.80 | SSTR5 (0.60) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL31709067 | 0.79 | KDM4E (0.65) | KDM4EALOX15CHRM2CHRM4CHRM5 | |
| SCHEMBL31709354 | 0.78 | ALDH1A1 (0.59) | KDM4EALOX15CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | KDM4E 2774/4885ALOX15 1853/4885CHRM2 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.