Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972297 | 0.80 | SMN1; SMN2 (0.39) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL22696331 | 0.80 | SMN1; SMN2 (0.39) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL20075810 | 0.80 | HTT (0.38) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL18398496 | 0.77 | HTT (0.36) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL29759333 | 0.74 | ALDH1A1 (0.42) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4663299 | 0.74 | ALDH1A1 (0.42) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20075807 | 0.74 | HTR6 (0.35) | HTTPOLBNOS3NOS1NOS2 | |
| SCHEMBL3208148 | 0.74 | CYP3A4 (0.37) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31206751 | 0.74 | CYP3A4 (0.37) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22715880 | 0.73 | CYP1A2 (0.36) | ALDH1A1MAPTSMN1; SMN2HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | HTT 1112/4885POLB 3003/4885ALDH1A1 959/4885 |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, STAT1, STAT5B | HTT 2728/4885POLB 3678/4885ALDH1A1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.