Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972297 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AKDM4EHTTPOLB | |
| SCHEMBL8037329 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL31709596 | 0.80 | HTT (0.36) | SMN1; SMN2KMT2AKDM4EHTTPOLB | |
| SCHEMBL22034265 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AKDM4EHTTPOLB | |
| SCHEMBL3948804 | 0.79 | CYP2D6 (0.37) | KMT2AKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL11001556 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2KMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL22034206 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AKDM4EHTTPOLB | |
| SCHEMBL15164737 | 0.77 | FFAR1 (0.36) | SMN1; SMN2KMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL24558933 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2KMT2AKDM4EHTTPOLB | |
| SCHEMBL24558660 | 0.76 | LMNA (0.36) | SMN1; SMN2KMT2AKDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | claimed |
| US-20240158390-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLMITED COMPANY (IE) | 2024-05-16 | — | — | US | disclosed |
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115838353-A | Synthetic method of 2,6-dichloro-4-ethylpyridin-3-amine | 山西永津集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-3972964-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-30 | — | — | EP | disclosed |
| CN-113874380-A | Other heteroaromatic compounds with anti-RSV activity | 爱尔兰詹森科学公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020234333-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020234333-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158390-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | MAVS, ZC3HAV1, RNASEH1 | SMN1; SMN2 547/4885KMT2A 3174/4885KDM4E 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.