Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.30 |
| ▸ | S100A10 | P60903 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709816 | 0.99 | KIF11 (0.32) | DRD2DRD4DRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL31710106 | 0.94 | HDAC6 (0.32) | — | |
| SCHEMBL31710411 | 0.94 | HDAC3 (0.32) | — | |
| SCHEMBL31709710 | 0.92 | TLR8 (0.35) | ALDH1A1KIF11TLR8P2RX7MEN1 | |
| SCHEMBL31709716 | 0.91 | KDM4E (0.36) | ALDH1A1KIF11TLR8P2RX7ANXA2 | |
| SCHEMBL26134634 | 0.89 | TLR8 (0.40) | ALDH1A1KIF11TLR8KDM4E | |
| SCHEMBL26125847 | 0.88 | KDM4E (0.41) | ALDH1A1TLR8KDM4E | |
| SCHEMBL26124979 | 0.88 | KDM4E (0.41) | ALDH1A1TLR8KDM4E | |
| SCHEMBL31710487 | 0.87 | KIF11 (0.37) | ALDH1A1KIF11P2RX7MEN1KMT2A | |
| SCHEMBL26135826 | 0.87 | TLR8 (0.34) | ALDH1A1KIF11TLR8ANXA2S100A10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | UNIV NORTH CAROLINA STATE (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | PGLS, ALG8, PFAS | DRD2 1365/4885DRD4 1346/4885DRD3 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.