Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.33 |
| ▸ | S100A10 | P60903 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709716 | 0.99 | KDM4E (0.36) | TLR8KIF11KDM4EALDH1A1ANXA2 | |
| SCHEMBL26134634 | 0.96 | TLR8 (0.40) | TLR8KIF11KDM4EALDH1A1CNR2 | |
| SCHEMBL26125847 | 0.95 | KDM4E (0.41) | TLR8KDM4EALDH1A1CNR2 | |
| SCHEMBL26124979 | 0.95 | KDM4E (0.41) | TLR8KDM4EALDH1A1CNR2 | |
| SCHEMBL31710487 | 0.95 | KIF11 (0.37) | KIF11KDM4EALDH1A1CCR1CCR2 | |
| SCHEMBL26135826 | 0.94 | TLR8 (0.34) | TLR8KIF11KDM4EALDH1A1ANXA2 | |
| SCHEMBL31710414 | 0.93 | TLR8 (0.34) | TLR8KIF11KDM4EALDH1A1ANXA2 | |
| SCHEMBL31709660 | 0.92 | DRD2 (0.33) | TLR8KIF11KDM4EALDH1A1ANXA2 | |
| SCHEMBL31709816 | 0.91 | KIF11 (0.32) | KIF11KDM4EALDH1A1ANXA2S100A10 | |
| SCHEMBL31710345 | 0.90 | MAOB (0.35) | TLR8KIF11ANXA2S100A10CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | UNIV NORTH CAROLINA STATE (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | PGLS, ALG8, PFAS | TLR8 290/4885KIF11 4542/4885KDM4E 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.