Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | STAMBP | O95630 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722502 | 0.81 | NNMT (0.43) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL31712859 | 0.81 | NNMT (0.48) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL29685869 | 0.80 | IP6K1 (0.39) | NNMTSMN1; SMN2HTR1BCHEK2 | |
| SCHEMBL26918319 | 0.80 | IP6K1 (0.39) | NNMTSMN1; SMN2HTR1BCHEK2 | |
| SCHEMBL26607639 | 0.73 | NNMT (0.47) | NNMTSMN1; SMN2PSMD14STAMBPCOPS5 | |
| SCHEMBL29875709 | 0.72 | LCK (0.35) | — | |
| SCHEMBL31712875 | 0.70 | KCNH2 (0.39) | — | |
| SCHEMBL31712852 | 0.69 | IP6K1 (0.36) | NNMTSMN1; SMN2HTR1BCHEK2 | |
| SCHEMBL24468601 | 0.69 | KDM4E (0.35) | PSMD14LMNA | |
| SCHEMBL29650949 | 0.69 | KDM4E (0.35) | PSMD14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |