Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 13/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875412 | 0.84 | MAPK1 (0.38) | METMAPK1MEN1KMT2A | |
| SCHEMBL29875709 | 0.77 | LCK (0.35) | — | |
| SCHEMBL26918319 | 0.76 | IP6K1 (0.39) | KCNH2ATM | |
| SCHEMBL29685869 | 0.76 | IP6K1 (0.39) | KCNH2ATM | |
| SCHEMBL31712856 | 0.70 | NNMT (0.40) | — | |
| SCHEMBL31064356 | 0.68 | NNMT (0.33) | — | |
| SCHEMBL24468115 | 0.67 | TBK1 (0.37) | MAPK1 | |
| SCHEMBL29650675 | 0.67 | TBK1 (0.37) | MAPK1 | |
| SCHEMBL31712852 | 0.65 | IP6K1 (0.36) | KCNH2ATMROCK2 | |
| SCHEMBL30707783 | 0.65 | AR (0.37) | KCNH2ATMMETCSF1RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |