Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23414986 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL29852457 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL31053388 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL2435352 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL30323375 | 0.77 | MAPK1 (0.49) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL31158416 | 0.74 | MAPK1 (0.42) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL21081513 | 0.74 | MAPK1 (0.46) | ALDH1A1MAPK1HPGDGAAHSD17B10 | |
| SCHEMBL31066451 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL23961101 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPK1KDM4EHPGDGAA | |
| SCHEMBL2436166 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPK1GAAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2025-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | ALDH1A1 3515/4885MAPK1 4120/4885KDM4E 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.