Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061788 | 0.67 | HSP90AB1 (0.44) | HTTNPC1RAB9AHSP90AA1ABCB1 | |
| SCHEMBL31265674 | 0.67 | ALDH1A1 (0.55) | HTTLMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL3278731 | 0.67 | ALDH1A1 (0.55) | HTTLMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL11191903 | 0.66 | HSP90AB1 (0.40) | NPC1RAB9AHSP90AA1ABCB1HSP90AB1 | |
| SCHEMBL11225658 | 0.66 | HSP90AB1 (0.40) | NPC1RAB9AHSP90AA1ABCB1HSP90AB1 | |
| SCHEMBL13798680 | 0.66 | CYP1A2 (0.39) | HTTLMNAHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL13798687 | 0.66 | CYP1A2 (0.30) | KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31715103 | 0.66 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL6034037 | 0.65 | ABCB1 (0.46) | HTTLMNANPC1RAB9AHSP90AA1 | |
| SCHEMBL30108079 | 0.65 | KMT2A (0.41) | LMNANPC1RAB9AHSP90AA1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2025-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | HTT 2131/4885LMNA 3393/4885BTK 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.