SCHEMBL31718018

SCHEMBL31718018

Ic1ccc(OCc2ccccc2)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 5/20 0.52
▸ GABRP O00591 1/20 0.45
▸ GABRD O14764 1/20 0.45
▸ GABRA1 P14867 1/20 0.45
▸ GABRB1 P18505 1/20 0.45
▸ GABRG2 P18507 1/20 0.45
▸ GABRB3 P28472 1/20 0.45
▸ GABRA5 P31644 1/20 0.45
▸ GABRA3 P34903 1/20 0.45
▸ GABRA2 P47869 1/20 0.45
▸ GABRB2 P47870 1/20 0.45
▸ GABRA4 P48169 1/20 0.45
▸ GABRE P78334 1/20 0.45
▸ GABRA6 Q16445 1/20 0.45
▸ GABRG1 Q8N1C3 1/20 0.45
▸ GABRG3 Q99928 1/20 0.45
▸ GABRQ Q9UN88 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ FFAR1 O14842 1/20 0.45
▸ LOXL2 Q9Y4K0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5954087 1.00 APP (0.52) APPGABRPGABRDGABRA1GABRB1
SCHEMBL18429675 0.89 APP (0.55) APP
SCHEMBL1187575 0.80 APP (0.65) APP
SCHEMBL198499 0.79 CYP1A2 (0.55) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL30454012 0.79 CYP1A2 (0.55) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL510168 0.78 GABRA5 (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16964639 0.78 GABRG2 (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL224083 0.78 MAOB (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL12203827 0.78 PKM (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4288596 0.78 PLAU (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460256-B1 Nucleotide analogs for efficient DNA and RNA amplification BENNER STEVEN A (US) 2025-11-04 — — US disclosed
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