Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198499 | 1.00 | CYP1A2 (0.55) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| Alcohol SCHEMBL29161613 | 0.93 | FFAR1 (0.51) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL1974540 | 0.84 | TSHR (0.44) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL1547117 | 0.83 | LMNA (0.64) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL510464 | 0.81 | FFAR1 (0.47) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| Methane SCHEMBL9237648 | 0.80 | CXCR2 (0.44) | LMNACXCR2PKMMEN1KMT2A | |
| SCHEMBL510168 | 0.79 | GABRA5 (0.52) | LMNAFFAR1CXCR2GABRPGABRD | |
| SCHEMBL16964639 | 0.79 | GABRG2 (0.45) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL12203827 | 0.79 | PKM (0.49) | LMNAFFAR1CXCR2GABRPGABRD | |
| SCHEMBL224083 | 0.79 | MAOB (0.56) | FFAR1CXCR2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046221-A1 | EGFR INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-03-07 | — | — | WO | disclosed |
| CN-111787916-B | Dihydroceramide desaturase inhibitors for treating diseases | 森陶鲁斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |