SCHEMBL31720173

SCHEMBL31720173

CC1(C)OB(c2ccc3nnn(CC(F)F)c3n2)OC1(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.30
LIPG Q9Y5X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31720496 0.81 SLC9A1 (0.30)
SCHEMBL26979177 0.75 LPL (0.38) LPLLIPG
SCHEMBL30725371 0.75 LPL (0.38) LPLLIPG
SCHEMBL30950801 0.71 CYP11B2 (0.33)
SCHEMBL31720195 0.68 ALDH1A1 (0.32)
SCHEMBL31469621 0.66 LPL (0.35) LPLLIPG
SCHEMBL31642521 0.66 IRAK4 (0.35) LPLLIPG
SCHEMBL25896892 0.64 IRAK4 (0.35) LPLLIPG
SCHEMBL31401223 0.63 LPL (0.40) LPLLIPG
SCHEMBL31394375 0.62 HTR2A (0.46) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340575-A1 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF BIOSPLICE THERAPEUTICS INC (US) 2025-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340575-A1 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF DYRK1A, DYRK2, DYRK1B LPL 4794/4885LIPG 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.