Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31722679 | 0.92 | DRD3 (0.45) | DRD3HPGDPARP1TNKSPARP10 | |
| SCHEMBL23134540 | 0.91 | PARP1 (0.43) | HRH3HPGDPARP1HTR4CHRM4 | |
| SCHEMBL23134692 | 0.89 | PARP1 (0.42) | HPGDPARP1HTR4SOS1MEN1 | |
| SCHEMBL30963364 | 0.88 | KDM4E (0.41) | PARP1TNKSPARP10TNKS2SOS1 | |
| SCHEMBL30963368 | 0.87 | DDB1 (0.42) | PARP1TNKSPARP10TNKS2SOS1 | |
| SCHEMBL31255475 | 0.82 | ALDH1A1 (0.42) | PARP1TNKSPARP10TNKS2SOS1 | |
| SCHEMBL30135826 | 0.81 | ALDH1A1 (0.53) | HPGDPARP1TNKSPARP10TNKS2 | |
| SCHEMBL23134536 | 0.81 | NR3C1 (0.42) | CRBNMEN1KMT2ATLR8TLR7 | |
| SCHEMBL21409284 | 0.81 | NR3C1 (0.42) | MEN1KMT2ATLR9TLR8TLR7 | |
| SCHEMBL21409448 | 0.81 | HSD11B1 (0.42) | MEN1KMT2ATLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228947-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 | CROSSFIRE ONCOLOGY B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |