SCHEMBL31723215

SCHEMBL31723215

Cc1cc(N)c(Cl)c(N(C)c2cccc(F)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.36
SLC6A2 P23975 4/20 0.33
SLC6A4 P31645 4/20 0.33
SLC6A3 Q01959 3/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
SNCA P37840 1/20 0.32
GPBAR1 Q8TDU6 1/20 0.32
CETP P11597 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
DHFR P00374 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454065 1.00 ACHE (0.37) ACHEABCG2SLC6A2SLC6A4SLC6A3
SCHEMBL22231968 1.00 ACHE (0.37) ACHEABCG2SLC6A2SLC6A4SLC6A3
SCHEMBL29454133 0.87 CSF1R (0.37) ACHEMAPK13MAPK12MAPK11MAPK14
SCHEMBL22232301 0.87 CSF1R (0.37) ACHEMAPK13MAPK12MAPK11MAPK14
SCHEMBL31723186 0.87 CSF1R (0.37) ACHEMAPK13MAPK12MAPK11MAPK14
SCHEMBL22232145 0.85 HTR3E (0.43) MAPK13MAPK12MAPK11MAPK14KMT2A
SCHEMBL31723251 0.85 HTR3E (0.43) MAPK13MAPK12MAPK11MAPK14KMT2A
SCHEMBL29454118 0.85 HTR3E (0.43) MAPK13MAPK12MAPK11MAPK14KMT2A
SCHEMBL31723220 0.85 NOS1 (0.32) SLC6A2SLC6A4SLC6A3NOS2
SCHEMBL29454059 0.85 NOS1 (0.32) SLC6A2SLC6A4SLC6A3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed