SCHEMBL31723220

SCHEMBL31723220

Cc1cc(N)c(Cl)c(N(C)c2cc(F)cc(F)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
APP P05067 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454059 1.00 NOS1 (0.32) NOS1NOS3NOS2SLC6A2SLC6A4
SCHEMBL22232037 0.92 RAPGEF4 (0.35) NOS1NOS3NOS2
SCHEMBL29454215 0.92 RAPGEF4 (0.35) NOS1NOS3NOS2
SCHEMBL31723207 0.92 RAPGEF4 (0.35) NOS1NOS3NOS2
SCHEMBL22232378 0.86 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3APP
SCHEMBL29454090 0.86 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3APP
SCHEMBL22231968 0.85 ACHE (0.37) NOS2SLC6A2SLC6A4SLC6A3
SCHEMBL31723215 0.85 ACHE (0.37) NOS2SLC6A2SLC6A4SLC6A3
SCHEMBL29454065 0.85 ACHE (0.37) NOS2SLC6A2SLC6A4SLC6A3
SCHEMBL31723191 0.80 MAPK13 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed