Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987315 | 0.77 | USP7 (0.45) | HSD17B13CDK9KDM4E | |
| SCHEMBL22831795 | 0.77 | BRAF (0.47) | HSD17B13SIGMAR1BRAFCYP2D6GRM1 | |
| SCHEMBL27453692 | 0.74 | HSD17B13 (0.42) | HSD17B13BRAFBRD4CDK9 | |
| SCHEMBL29281526 | 0.74 | HSD17B13 (0.41) | HSD17B13BRAFBRD4CDK9 | |
| SCHEMBL24879033 | 0.73 | CLK1 (0.48) | HSD17B13BRAFGRM1KDM4E | |
| Hydrochloric Acid SCHEMBL29743558 | 0.72 | ACHE (0.49) | CYP2D6DRD2 | |
| SCHEMBL27216075 | 0.71 | CYP11B2 (0.42) | HSD17B13BRAFBRD4CDK9 | |
| SCHEMBL31723352 | 0.71 | BRAF (0.38) | HSD17B13BRAF | |
| SCHEMBL24879123 | 0.71 | BRAF (0.46) | HSD17B13BRAFKDM4E | |
| SCHEMBL8279991 | 0.70 | HSD17B13 (0.48) | HSD17B13SIGMAR1BRD4CDK9CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |