Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 10/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725014 | 0.94 | CNR2 (0.48) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL8377397 | 0.82 | HSD17B10 (0.58) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL31725139 | 0.78 | KCNH2 (0.51) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL8377366 | 0.78 | PDK2 (0.46) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL8377376 | 0.77 | PDK2 (0.46) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL25470614 | 0.76 | SCN9A (0.50) | HPGDALDH1A1RAB9APDK2SCN9A | |
| SCHEMBL31296532 | 0.76 | SCN9A (0.50) | HPGDALDH1A1RAB9APDK2SCN9A | |
| SCHEMBL8380157 | 0.76 | PDK2 (0.48) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL8375694 | 0.76 | NQO2 (0.44) | HPGDHSD17B10ALDH1A1RAB9AKDM4E | |
| SCHEMBL31724954 | 0.75 | RAB9A (0.42) | HPGDHSD17B10ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346587-A1 | NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC DERIVATIVES AS CHECKPOINT KINASE 1 INHIBITOR AND USES THEREOF | SPEROGENIX THERAPEUTICS LTD (CN) | 2025-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346587-A1 | NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC DERIVATIVES AS CHECKPOINT KINASE 1 INHIBITOR AND USES THEREOF | CHEK1, CHEK2, BUB1 | HPGD 1720/4885HSD17B10 2812/4885ALDH1A1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.